- Harold rises to the level of a caravan boss in the Hub. His caravans suffer occasional attacks in the wastes, but Harold's caravan outfit survives and prospers... until the mutant attacks begin to pick up a few years later[12].
- A man named Jonathan Faust leads his group of about 200 people from the overcrowded Vault 15 into the wastes of the outside. Eventually they become a raider band known as the Vipers[40].
- The Vault City Overseer retires and the Council of Citizens is established. The Council appoints the initial First Citizen[41].
- May 22: Increasing mutant attacks on Harold's caravans cause Harold to get so upset he finances one of the first adventuring parties of Fallout to try and find out where the mutants are coming from. Consulting with a scientist and doctor at the Hub, a man by the name of Grey, the two of them decide to join forces[12].
- June 23: Richard Grey's Expedition [including Harold] finds the Mariposa Military Base and the Expedition is scattered and defeated by mutants at the base. Grey is knocked into one of the vats of FEV by a robotic arm, and Harold is knocked unconscious, only to awaken later out in the wasteland[12].
- June 27: Harold, already mutating, is found by traders and taken back to the Hub. His former caravan partners and employees, horrified by his condition, abandon him and he is soon left[12].
- July: Richard Grey, now horribly mutated by the virus, crawls from the Vats covered with FEV and in terrible pain. Barely able to think or perceive his surroundings, he crawls into the Vat control room and begins his audio log. He fades in and out of consciousness, sometimes for days or weeks at a time[12].
- July-November: Richard Grey begins to acclimate to his condition, and begins his first tests of animals by exposing them to FEV. These experiments and his growing awareness lay the foundation for his plans for the Unity and the master race. He takes the name, "the Master."[12].
- November: The first human victim wanders into Mariposa, and Grey consumes him[12].
- December: Grey continues his experiments on wanderers that enter Mariposa... with no success. The creations are flawed (due to the radiation counts in their bodies), making them big but incredibly stupid, and Grey consumes them rather than letting them live[12].
- January: The Master discovers the problem with the influence of radiation on his mutations, and he begins to choose his subjects more carefully. The first classic super mutants are born. He begins his plans to build an army[12].
- 2103-2130: Throughout this period, the Master begins slowly gathering test subjects, willing or unwilling, from local human stock. The Great Winter of 2130 and the scarcity of human subjects make building his army difficult[12].
- Angus rules over growing Hub and establishes himself as governor[12].
- The Vipers' attempt to raid the Hub is stopped almost solely by Angus. Angus' defense causes the Vipers to retreat north[40]
- Winter: Angus is murdered. Hub is thrown into chaos[12].
- A band of merchants seizes the water tower in the Hub. They demand anyone wanting water must pay a toll. The Great Merchant Wars begin[12].
- 2126-2128: The Great Merchant Wars are fought, the Water Merchants seal up the town, but are outnumbered[12].
- A man named Roy Greene (Justin Greene's grandfather) makes the peace in the Hub and negotiates a settlement. The Hub's Central Council is formed, composed of two representatives from each of the Hub caravan companies. A long period of indecisiveness and meetings maintain the status quo in the Hub[12].